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DATA DOWNLOADRecombinant human Utrophin
DHTX; Disrupted in heterotaxy; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance associated gene protein; UV radiation resistance-associated gene protein; Utrophin; Utrophin_HUMAN.
浓度:1mg/ ml
来源:Recombinant Human
纯度:≥95% SDS-PAGE
表达系统:Wheat germ
标签:GST tag N-Terminus
蛋白长度:Protein fragment
内毒素水平:<1.000 Eu/µg
纯化方法:HPLC
应用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保质期:1年
Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.
抗体
产品名称:Rabbit Anti-Utrophin antibody
Rabbit Anti-Utrophin
别名:DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin
来源:Rabbit
克隆类型:Polyclonal
浓度:1mg/ml
亚型:IgG
应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反应:Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Chicken,Dog)
理论分子量:394kDa
免疫原:KLH conjugated synthetic peptide derived from Human Utrophin
保存:-20℃
保质期:1年
单克隆抗体
产品名称:Anti-Utrophin antibody
Mouse Anti-Utrophin
别名:DMDL; DRP 1; DRP; DRP-1; DRP1; Dystrophin like protein; Dystrophin related protein 1; Dystrophin related protein; Dystrophin-related protein 1; FLJ23678; UTRN; UTRO_HUMAN; Utrophin (homologous to dystrophin); Utrophin
来源:Mouse
克隆类型:Monoclonal
浓度:1mg/ml
亚型:IgG
应用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反应: Human
理论分子量:394kDa
免疫原:KLH conjugated synthetic peptide derived from Human Utrophin
保存:-20℃
保质期:1年
Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.