VSIG4抗原，T淋巴细胞负调节蛋白抗原

Recombinant human VSIG4 protein   

V-set and immunoglobulin domain-containing protein 4; CRIg; V set and immunoglobulin domain containing 4; Z39IG; VSIG4_HUMAN.  

浓度：1mg/ ml

来源：Recombinant Human

纯度：≥95% SDS-PAGE

表达系统：HEK 293 cells

标签：His tag C-Terminus   

蛋白长度：Full length protein

内毒素水平：<1.000 Eu/µg

纯化方法：HPLC

应用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保质期：1年

T cell activation by APCs is positively and negatively regulated by members of the B7 family. We have identified a previously unknown function for B7 familyrelated protein V-set and Ig domaincontaining 4 (VSIG4). Administration to mice of soluble VSIG4-Ig fusion molecules reduced the induction of T cell responses in vivo and inhibited the production of Th celldependent IgG responses. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.

产品名称：Rabbit Anti-VSIG4 protein antibody

Rabbit Anti-VSIG4 protein 

别名：V-set and immunoglobulin domain-containing protein 4; CRIg; V set and immunoglobulin domain containing 4; Z39IG; VSIG4_HUMAN.                 

来源：Rabbit

克隆类型：Polyclonal

浓度：1mg/ml

亚型：IgG

反应：Mouse,Rat (predicted: Human,Cow,Dog)

应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

理论分子量：33kDa

免疫原：KLH conjugated synthetic peptide derived from human VSIG4 protein

保存：-20℃
保质期：1年

产品名称：Anti-VSIG4 protein antibody

Mouse Anti-VSIG4 protein

别名：V-set and immunoglobulin domain-containing protein 4; CRIg; V set and immunoglobulin domain containing 4; Z39IG; VSIG4_HUMAN.                    

来源：Mouse

克隆类型：Monoclonal

浓度：1mg/ml

亚型：IgG

反应：Human

应用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反应:  Human

理论分子量：33kDa

免疫原：KLH conjugated synthetic peptide derived from human VSIG4  

保存：-20℃
保质期：1年

T cell activation by APCs is positively and negatively regulated by members of the B7 family. We have identified a previously unknown function for B7 familyrelated protein V-set and Ig domaincontaining 4 (VSIG4). Administration to mice of soluble VSIG4-Ig fusion molecules reduced the induction of T cell responses in vivo and inhibited the production of Th celldependent IgG responses. Unlike that of B7 family members, surface expression of VSIG4 was restricted to resting tissue macrophages and absent upon activation by LPS or in autoimmune inflammatory foci. The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.