WIF1抗原，Wnt信号抑制因子1抗原

Recombinant human WIF1   

WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.  

浓度：1mg/ ml

来源：Recombinant Human

纯度：≥95% SDS-PAGE

表达系统：HEK 293 cells

标签：His tag C-Terminus   

蛋白长度：Full length protein

内毒素水平：<1.000 Eu/µg

纯化方法：HPLC

应用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保质期：1年

The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.

产品名称：Rabbit Anti-WIF1 antibody

Rabbit Anti-WIF1 

别名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.              

来源：Rabbit

克隆类型：Polyclonal

浓度：1mg/ml

亚型：IgG

反应：(predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)

应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

理论分子量：39kDa

免疫原：KLH conjugated synthetic peptide derived from human WIF1

保存：-20℃
保质期：1年

产品名称：Anti-WIF1 antibody

Mouse Anti-WIF1

别名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.                 

来源：Mouse

克隆类型：Monoclonal

浓度：1mg/ml

亚型：IgG

反应：Human

应用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反应:  Human

理论分子量：39kDa

免疫原：KLH conjugated synthetic peptide derived from human WIF1

保存：-20℃
保质期：1年

The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.