XRN1抗原，XRN1蛋白抗原

Recombinant human XRN1   

XRN1_HUMAN; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.       

浓度：1mg/ ml

来源：Recombinant Human

纯度：≥95% SDS-PAGE

表达系统：Escherichia coli

标签：His tag   

蛋白长度：Full length protein

内毒素水平：<1.000 Eu/µg

纯化方法：HPLC

应用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保质期：1年

Lamins are type V intermediate filament proteins and are grouped into constitutively expressed B-type lamins and developmentally regulated A-type lamins. Lamin-binding proteins in the nuclear lamina and the nuclear interior include several protein families and/or types of proteins in higher eukaryotes such as the inner nuclear membrane proteins, lamin B receptor, emerin, MANI, three isoforms of lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to six LAP 2 isoforms derive from a single gene by alternative splicing in mammals and various isoforms have been described in Xenopus. The best characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta and the nucleoplasmic protein LAP 2 alpha, which are identical in their N-terminal 187-amino acid constant region but differ in their C termini. LAP 2 alpha specifically interacts with A-type lamins within the nuclear interior as part of a detergent- and salt-resistant nucleoskeletal structure.

多克隆抗体

产品名称：Rabbit Anti-XRN1 antibody

Rabbit Anti-XRN1 

别名：XRN1_HUMAN; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.              

来源：Rabbit

克隆类型：Polyclonal

浓度：1mg/ml

亚型：IgG

反应：Human,Mouse,Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Orangutan

应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

理论分子量：193kDa

免疫原：KLH conjugated synthetic peptide derived from human XRN1

保存：-20℃
保质期：1年

 单克隆抗体

产品名称：Anti-XRN1 antibody

Mouse Anti-XRN1

别名：XRN1_HUMAN; Dhm2; mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.               

来源：Mouse

克隆类型：Monoclonal

浓度：1mg/ml

亚型：IgG

反应：Human

应用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500  

反应:  Human

理论分子量：193kDa

免疫原：KLH conjugated synthetic peptide derived from human XRN1

保存：-20℃
保质期：1年

This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.